March 31 2017DOCOMOMO US National Symposium visit

first_imgMarch 31, 2017DOCOMOMO US National Symposium visits Arcosanti.The Docomomo US National Symposium is the primary event in the United States for professionals to discuss and share efforts to preserve modern architecture and meet leading practitioners and industry professionals.[photos by Leah-Ann Walker]The Fifth Annual Docomomo US National Symposium entitled “Modernism and Climate” is taking place in Phoenix, AZ from March 29. through April 2. 2017.It will look at how modern design approached desert climates creatively and how thos design strategies continue to be relevant in light of our search for sustainable solutions and what can be learned from those creative efforts.The only national event dedicated to all aspects of the preservation of Modernism, the symposium brings together world renowned designers, scholars, students and professionals from around the country.last_img read more

The DTG has released DBook 10 the latest specifi

first_imgThe DTG has released D-Book 10, the latest specification for UK television that is designed to enable to the continuing transition towards HbbTV.D-Book 10 is an industry determined, next-generation specification, which supports future interactive services and marks an update to D-Book 9.Among the updates contained in D-Book 10 is the introduction of Single Frequency Network (SFN) support for the migration of COM 7&8 T2 multiplexes into the 700 MHz band.An ‘IP Software Upgrade Option’ has also been included in response to manufacturer requirements for software upgrades to today’s complex TVs, avoiding the need for SSU Broadcast updates.“The DTG team thanks all of our members whose hard work has contributed to D-Book 10,” said Richard Lindsay-Davies, CEO of the DTG.“Open, democratic and supportive of public policy, the DTG’s D-Book is continually updated and peer-reviewed by industry experts, to help drive the UK TV market towards innovation and deliver real economic value in our industry.”“It stipulates the specifications for every new TV and digital terrestrial television (DTT) receiver in the UK and protects both viewer and industry. We’ve been driving industry collaboration for more than twenty years and I’d like to thank the industry for its continued support and commitment to ensuring innovation and development which delivers a great experience for consumers.”Klaus Illgner, chair of the HbbTV Association, said: “The HbbTV association would like to congratulate DTG on the publication of D-Book 10 and its continued support for HbbTV 2.0.1. We believe the planned development of a code of practice for the implementation of interactive services will greatly benefit the quality of HbbTV services in the UK and beyond.”The DTG is a UK collaboration centre for innovation in digital media technology. It was set up in 1995 to look after the digital TV marketplace and it underpins the free-to-air platforms Freeview, Freesat and YouView.last_img read more

Novel personalized medicine tool for assessing inherited colorectal cancer syndrome risk developed

first_img Source:https://huntsmancancer.org/newsroom/2018/12/researchers-develop-personalized-medicine-tool-for-inherited-colorectal-cancer-syndrome-risk.php Reviewed by Alina Shrourou, B.Sc. (Editor)Dec 10 2018An international team of researchers led by Huntsman Cancer Institute (HCI) at the University of Utah (U of U) has developed, calibrated, and validated a novel tool for identifying the genetic changes in Lynch syndrome genes that are likely to be responsible for causing symptoms of the disease. The results were published this week in the journal Genetics in Medicine.Lynch syndrome is a hereditary condition that results in higher rates of colon, endometrial, and other cancers. If unmanaged, individuals with Lynch syndrome have a 75 percent lifetime risk of developing colorectal cancer. It is believed that approximately five percent of all colorectal cancer cases are associated with this syndrome.Millions of distinct changes are possible in genes that control health, and it is a massive undertaking to identify which specific changes are associated with developing disease. Some genetic changes are believed to have no impact at all, while others carry significant risk.Researchers at Huntsman Cancer Institute work to understand and classify which gene changes are likeliest to cause disease, as well as to identify appropriate strategies to help manage disease risk.This groundbreaking study was led by Sean Tavtigian, PhD, a cancer researcher at HCI and professor of oncological sciences at the U of U. The work was built on a decade-long international collaboration. “Correctly identifying which of the genetic changes we observe actually result in disease is fundamentally important in clinical care,” said Tavtigian. “Having clarity on this issue has the potential to add years to patients’ lives, reduce anxiety about disease risk, and use health care dollars more efficiently.”Related StoriesAdding immunotherapy after initial treatment improves survival in metastatic NSCLC patientsSugary drinks linked to cancer finds studyCancer killing capability of lesser-known immune cells identifiedThe team used a laboratory test previously developed by the group of Niels de Wind, PhD, associate professor of human genetics at the Leiden University Medical Center in The Netherlands, to characterize genetic changes associated with disease risk. The lab test, called the Cell-free in vitro MMR Activity (CIMRA) assay, improves classification of variants of uncertain significance in Lynch syndrome. “The test is rapid and accurate,” said de Wind. In the current study, the test was thoroughly calibrated and validated, such that its results could now be integrated with computer-based modeling and clinical data. As a result, this study provides an analytical tool suitable for clinical use to assess the potential of changes in Lynch syndrome genes to cause disease.”A key point is that we believe the accuracy of the tool combining the CIMRA test with the previously published computational analysis to be about 97 percent, making it appropriate for clinical use,” said Tavtigian. de Wind added that the work “represents a new pinnacle in the classification of genetic variation.”The authors believe that routine utilization of their methods will dramatically increase the rate of risk classification for genetic changes that previously were poorly understood. Moreover, this calibration strategy provides a template for the development, validation, and calibration of reliable strategies for the diagnostic assessment of other hereditary cancer predisposition syndromes and genetic disorders.last_img read more

Measures of biochemical hypoglycemia linked to high risk of severe hypoglycemic events

first_imgReviewed by James Ives, M.Psych. (Editor)Jan 10 2019Researchers have shown that measures of biochemical hypoglycemia in fingerstick blood samples are associated with an increased risk of severe hypoglycemic events. The results of this new study, which further emphasize the dangers of hypoglycemic blood glucose levels, are published in Diabetes Technology & Therapeutics (DTT), a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. Click here to read the full-text article free on the Diabetes Technology & Therapeutics (DTT) website through February 9, 2019.Related StoriesUranium toxicity might have caused obesity and diabetes in Kuwait, finds new studyAADE’s comprehensive guidance on care of children, young adults with diabetes releasedDiabetes patients experiencing empathy from PCPs have beneficial long-term clinical outcomesRoy Beck, MD, PhD, Jaeb Center for Health Research (Tampa, FL), Richard Bergenstal, MD, International Diabetes Center Park Nicollet (Minneapolis, MN), and Tonya Riddlesworth, PhD and Craig Kollman, PhD, Jaeb Center for Health Research, present their findings in the article entitled “The Association of Biochemical Hypoglycemia with the Subsequent Risk of a Severe Hypoglycemic Event: Analysis of the DCCT Data Set.” The researchers used two different levels of biochemical hypoglycemia – <70 or <54 mg/dL - to determine the relationship to severe hypoglycemic events. When either level was present, the risk of severe hypoglycemic events was significantly higher."Severe hypoglycemia is a significant hurdle for intensifying insulin therapy in patients with T1D. Beck and colleagues emphasize the increased risk of future severe hypoglycemia in patients with any level of biochemical hypoglycemia," says DTT Editor-in-Chief Satish Garg, MD, Professor of Medicine and Pediatrics at the University of Colorado Denver (Aurora).Source: https://home.liebertpub.com/news/new-data-emphasize-importance-of-avoiding-hypoglycemic-glucose-levels-in-type-1-diabetes/3492last_img read more

Grand alliance has neither leader nor policies Modi

first_imgMayawati sets riders for alliance with Congress in poll-bound States September 09, 2018 Published on politics Poll-mode Prime Minister Narendra Modi (right) and BJP President Amit Shah at the party’s National Executive meeting in New Delhi on Sunday   –  PTI Can ally with TDP in Telangana: Congress PM asks party workers to expose ‘Opposition’s falsehood’ Both Prime Minister Narendra Modi and BJP president Amit Shah expressed confidence that the BJP will retain power in 2019 and urged party workers to bust the Opposition’s “lies” by doing proper homework. Modi said the grand alliance against the BJP will be defeated as it neither has a leader nor a set of policies. Addressing the BJP national executive meeting here on Sunday, Modi said the aim is to create an India that cannot be subjugated and a BJP that remains atal (firm). Talking to reporters after the meeting, Law Minister Ravi Shankar Prasad said Modi told the meeting that the BJP is using power for change and development. “Gujarat is an example. We don’t see power as an instrument to occupy the chair, but we see it as a work to empower people with dedication,” Prasad said quoting Modi.He said the BJP’s work is based on principles. “We change our tactics from time to time. We don’t see a challenge. In a democracy, there must be an Opposition. But those who failed in the government have also failed as an Opposition. They haven’t raised any real issues. We are ready to take questions on our work,” Prasad said. “Let’s ask questions on 48 years of family rule and 48 months of a party’s rule. The comparison will reveal whom they were working for,” Prasad said.Modi also told the meeting that the Opposition’s campaigns are based on falsehood. “This must be defeated firmly with the great work we have done in the last four years,” Modi said. center_img COMMENTS SHARE SHARE EMAIL COMMENT SHARE RELATED last_img read more